5ouk: Difference between revisions
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==Crystal structure of human AKR1B1 complexed with NADP+ and compound 41== | ==Crystal structure of human AKR1B1 complexed with NADP+ and compound 41== | ||
<StructureSection load='5ouk' size='340' side='right' caption='[[5ouk]], [[Resolution|resolution]] 0.96Å' scene=''> | <StructureSection load='5ouk' size='340' side='right' caption='[[5ouk]], [[Resolution|resolution]] 0.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5ouk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OUK FirstGlance]. <br> | <table><tr><td colspan='2'>[[5ouk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OUK FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AVT:2-[5- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AVT:2-[9-fluoranyl-5-(4-methoxyphenyl)-3-methyl-1-oxidanylidene-pyrimido[4,5-c]quinolin-2-yl]ethanoic+acid'>AVT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4igs|4igs]], [[5ou0|5ou0]], [[5ouj|5ouj]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4igs|4igs]], [[5ou0|5ou0]], [[5ouj|5ouj]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ouk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ouk OCA], [http://pdbe.org/5ouk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ouk RCSB], [http://www.ebi.ac.uk/pdbsum/5ouk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ouk ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ouk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ouk OCA], [http://pdbe.org/5ouk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ouk RCSB], [http://www.ebi.ac.uk/pdbsum/5ouk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ouk ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
[[Category: Human]] | |||
[[Category: Cousido-Siah, A]] | [[Category: Cousido-Siah, A]] | ||
[[Category: Metwally, K]] | [[Category: Metwally, K]] | ||