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====Structure and interaction with the antiviral====
====Structure and interaction with the antiviral====


The new experimental antirviral, here the (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid, interacts with <scene name='80/802676/Site_of_interaction/1'>the site which bind to the LEDGF/p75 cofactor</scene>. This site is situated in the core domain.
The new experimental antirviral, here the (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid, interacts with <scene name='80/802676/Site_of_interaction/4'>the site which bind to the LEDGF/p75 cofactor</scene>. This site is situated in the core domain.
The molecule  
The molecule then inhibits the interaction between the LEDGF/p75 cofactor and the integrase.




Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA, Severine Perrin