Polycomb proteins: Difference between revisions
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== Function == | == Function == | ||
Polycomb group (PcG) proteins are determinants of gene silencing and epigenetic memory in higher eukaryotes. The PcG system consists of multimeric repressive protein complexes containing chromatin modifying activities which regulate transcription by modulating chromatin structures. The PcG proteins regulate pathways in cell differentiation, tissue regeneration and cancer cell growth<ref>PMID:27705803</ref>. | Polycomb group (PcG) proteins are determinants of gene silencing and epigenetic memory in higher eukaryotes. The PcG system consists of multimeric repressive protein complexes containing chromatin modifying activities which regulate transcription by modulating chromatin structures. The PcG proteins regulate pathways in cell differentiation, tissue regeneration and cancer cell growth<ref>PMID:27705803</ref>. For the '''B'''-cell-specific '''M'''olony leukemia virus '''I'''nsertion site '''1''' (BMI1) see [[BMI1]]. | ||
== Disease == | == Disease == | ||