3cro: Difference between revisions
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|PDB= 3cro |SIZE=350|CAPTION= <scene name='initialview01'>3cro</scene>, resolution 2.500Å | |PDB= 3cro |SIZE=350|CAPTION= <scene name='initialview01'>3cro</scene>, resolution 2.500Å | ||
|SITE= | |SITE= | ||
|LIGAND= | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cro OCA], [http://www.ebi.ac.uk/pdbsum/3cro PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3cro RCSB]</span> | |||
}} | }} | ||
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==About this Structure== | ==About this Structure== | ||
3CRO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ | 3CRO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Phage_434 Phage 434]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CRO OCA]. | ||
==Reference== | ==Reference== | ||
The phage 434 Cro/OR1 complex at 2.5 A resolution., Mondragon A, Harrison SC, J Mol Biol. 1991 May 20;219(2):321-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2038059 2038059] | The phage 434 Cro/OR1 complex at 2.5 A resolution., Mondragon A, Harrison SC, J Mol Biol. 1991 May 20;219(2):321-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2038059 2038059] | ||
[[Category: | [[Category: Phage 434]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Harrison, S C.]] | [[Category: Harrison, S C.]] | ||
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[[Category: protein-dna complex]] | [[Category: protein-dna complex]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:32:43 2008'' | ||
Revision as of 05:32, 31 March 2008
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| , resolution 2.500Å | |||||||
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| Ligands: | , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION
OverviewOverview
The crystal structure of phage 434 Cro protein in complex with a 20 base-pair DNA fragment has been determined to 2.5 A resolution. The DNA fragment contains the sequence of the OR1 operator site. The structure shows a bent conformation for the DNA, straighter at the center and more bent at the ends. The central base-pairs adopt conformations with significant deviations from coplanarity. The two molecules interact extensively along their common interface, both through hydrogen bonds and van der Waals interactions. The significance of these interactions for operator binding and recognition is discussed.
About this StructureAbout this Structure
3CRO is a Single protein structure of sequence from Phage 434. Full crystallographic information is available from OCA.
ReferenceReference
The phage 434 Cro/OR1 complex at 2.5 A resolution., Mondragon A, Harrison SC, J Mol Biol. 1991 May 20;219(2):321-34. PMID:2038059
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