Sandbox Reserved 1474: Difference between revisions
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====Cross reactions in vitro ligand binding studies==== | ====Cross reactions in vitro ligand binding studies==== | ||
It did not bind endogenous neurotransmitters or other medications and was not bound by protein C1q, thus it is unlikely to stimulate in vivo complement-dependent cytotoxicity. <ref name="Preclinical characterization of an anti-methamphetamine monoclonal antibody for human use" /> | It did not bind endogenous neurotransmitters or other medications and was not bound by protein C1q, thus it is unlikely to stimulate in vivo complement-dependent cytotoxicity. <ref name="Preclinical characterization of an anti-methamphetamine monoclonal antibody for human use" /> | ||
Table 2 <ref name="Preclinical characterization of an anti-methamphetamine monoclonal antibody for human use" />Ligands tested in Ch-mAb7F9 cross-reactivity study | Table 2 <ref name="Preclinical characterization of an anti-methamphetamine monoclonal antibody for human use" /> | ||
<table><tr><td colspan='2'> Ligands tested in Ch-mAb7F9 cross-reactivity study<ref name="Preclinical characterization of an anti-methamphetamine monoclonal antibody for human use" />.<br></td></tr> | |||
<tr id='Related stimulates'><td class="sblockLbl"><b>Related stimulates</b></td><td class="sblockDat"> (+)-Methamphetamine | |||
(+)-Amphetamine | |||
(+)-MDMA | |||
(-)-MDMA | |||
(+)-MDA</td></tr> | |||
<tr id='Neurotransmitters'> | |||
<td class="sblockLbl"><b>neurotransmitters </b></td><td class="sblockDat"> Dopamine | |||
(-)-Norepinephrine | |||
(-)-Epinephrine | |||
Serotonin | |||
γ-aminobutyric acid | |||
L-Glutamate | |||
</td></tr> | |||
<tr id='Medications'><td class="sblockLbl"><b>Medications </b></td><td class="sblockDat"> (+)-Pseudoephedrine | |||
(+)-Norpseudoephedrine | |||
(-)-Phenylephrine | |||
(±)-Ephedrine | |||
2-Phenylethylamine | |||
Tyramine | |||
</td></tr> | |||
<tr id='Drugs of abuse'><td class="sblockLbl"><b>Drugs of abuse </b></td><td class="sblockDat">Cocaine | |||
Morphine | |||
Phencyclidine | |||
</td></tr> | |||
</table> | |||