3b7o: Difference between revisions

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|PDB= 3b7o |SIZE=350|CAPTION= <scene name='initialview01'>3b7o</scene>, resolution 1.60&Aring;
|PDB= 3b7o |SIZE=350|CAPTION= <scene name='initialview01'>3b7o</scene>, resolution 1.60&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=MLT:MALATE ION'>MLT</scene>
|LIGAND= <scene name='pdbligand=MLT:MALATE+ION'>MLT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
|GENE= PTPN11, PTP2C, SHPTP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= PTPN11, PTP2C, SHPTP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2shp|2SHP]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7o OCA], [http://www.ebi.ac.uk/pdbsum/3b7o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b7o RCSB]</span>
}}
}}


'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site'''
'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site'''


==Disease==
Known diseases associated with this structure: Leopard syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Leukemia, juvenile myelomonocytic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Noonan syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]]


==About this Structure==
==About this Structure==
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[[Category: Ugochukwu, E.]]
[[Category: Ugochukwu, E.]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: MLT]]
[[Category: alternative splicing]]
[[Category: alternative splicing]]
[[Category: cytoplasm]]
[[Category: cytoplasm]]
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[[Category: tyrosine phosphatase]]
[[Category: tyrosine phosphatase]]


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