3ec8: Difference between revisions

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==The crystal structure of the RA domain of FLJ10324 (RADIL)==
==The crystal structure of the RA domain of FLJ10324 (RADIL)==
<StructureSection load='3ec8' size='340' side='right' caption='[[3ec8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='3ec8' size='340' side='right' caption='[[3ec8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<table><tr><td colspan='2'>[[3ec8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EC8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ec8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EC8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ec8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ec8 OCA], [http://pdbe.org/3ec8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ec8 RCSB], [http://www.ebi.ac.uk/pdbsum/3ec8 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ec8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ec8 OCA], [http://pdbe.org/3ec8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ec8 RCSB], [http://www.ebi.ac.uk/pdbsum/3ec8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ec8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/3ec8_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/3ec8_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>

Revision as of 00:48, 3 December 2018

The crystal structure of the RA domain of FLJ10324 (RADIL)The crystal structure of the RA domain of FLJ10324 (RADIL)

Structural highlights

3ec8 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[RADIL_HUMAN] Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Smolen GA, Schott BJ, Stewart RA, Diederichs S, Muir B, Provencher HL, Look AT, Sgroi DC, Peterson RT, Haber DA. A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors. Genes Dev. 2007 Sep 1;21(17):2131-6. Epub 2007 Aug 17. PMID:17704304 doi:http://dx.doi.org/gad.1561507

3ec8, resolution 2.60Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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