6bp9: Difference between revisions

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-'''Unreleased structure'''
-The entry 6bp9 is ON HOLD  until Paper Publication
+==HSPB5 alpha-crystallin domain mutant R120G-ACD==
+<StructureSection load='6bp9' size='340' side='right' caption='[[6bp9]], [[NMR_Ensembles_of_Models | 8 NMR models]]' scene=''>
-Authors: Rajagopal, P., Klevit, R.E.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6bp9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BP9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BP9 FirstGlance]. <br>
-Description: HSPB5 alpha-crystallin domain mutant R120G-ACD
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRYAB, CRYA2, HSPB5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bp9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bp9 OCA], [http://pdbe.org/6bp9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bp9 RCSB], [http://www.ebi.ac.uk/pdbsum/6bp9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bp9 ProSAT]</span></td></tr>
-[[Category: Klevit, R.E]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN]] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN]] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
+__TOC__
+</StructureSection>
+[[Category: Human]]
+[[Category: Klevit, R E]]
 [[Category: Rajagopal, P]]
+[[Category: Cataract-causing heat shock protein alpha-crystallin b chain beta sandwich]]
+[[Category: Chaperone]]