Sandbox Reserved 1456: Difference between revisions
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<StructureSection load='4rbm' size='340' side='right' caption='Structure of Kgp' scene=''> | <StructureSection load='4rbm' size='340' side='right' caption='Structure of Kgp' scene=''> | ||
== <scene name='79/799584/Rainbow_all_protein/ | == <scene name='79/799584/Rainbow_all_protein/6'>Function</scene> == | ||
The protein, Kgp, is being studied in the bacteria ''Porphyromonas gingivalis''. Kgp is a virulence factor of ''P. gingivalis'' that cleaves many constituents of connective tissue, leading to decreased bactericidal activity and chronic inflammation of the gums. Virulence is due to nutrient acquisition, cleavage of host cell surface receptors, signaling via protease activated receptors, and inactivation of cytokines and of the complement system. | The protein, Kgp, is being studied in the bacteria ''Porphyromonas gingivalis''. Kgp is a virulence factor of ''P. gingivalis'' that cleaves many constituents of connective tissue, leading to decreased bactericidal activity and chronic inflammation of the gums. Virulence is due to nutrient acquisition, cleavage of host cell surface receptors, signaling via protease activated receptors, and inactivation of cytokines and of the complement system. | ||