6euc: Difference between revisions
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==Reactivating oxime bound to Tc AChE's catalytic gorge.== | |||
<StructureSection load='6euc' size='340' side='right' caption='[[6euc]], [[Resolution|resolution]] 2.22Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6euc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EUC FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RM0:2-[(~{E})-hydroxyiminomethyl]-6-(5-morpholin-4-ylpentyl)pyridin-3-ol'>RM0</scene></td></tr> | |||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6euc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6euc OCA], [http://pdbe.org/6euc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6euc RCSB], [http://www.ebi.ac.uk/pdbsum/6euc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6euc ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Acetylcholinesterase]] | |||
[[Category: Braiki, A]] | [[Category: Braiki, A]] | ||
[[Category: Jean, L]] | |||
[[Category: Mora, E de la]] | |||
[[Category: Mougeot, R]] | [[Category: Mougeot, R]] | ||
[[Category: | [[Category: Renard, P I]] | ||
[[Category: Weik, M]] | [[Category: Weik, M]] | ||
[[Category: Aldehyde oxime]] | |||
[[Category: Hydrolase]] | |||
[[Category: Organophosphate poisoning]] | |||
[[Category: Reactivator]] | |||
Revision as of 11:17, 14 November 2018
Reactivating oxime bound to Tc AChE's catalytic gorge.Reactivating oxime bound to Tc AChE's catalytic gorge.
Structural highlights
Function[ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions. |
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