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==Experimental results==
==Experimental results==
Heterozygous mutation facilitates tumor development and homozygous mutation is embryonically lethal in a mouse model where p53 is targeted deleted in the mammary gland and BRCA1 deletion is varied according to the required zygosity <ref>pmid 22172724</ref>. High impact in yeast two-hybrid assay <ref name='p16403807'/></ref>.
Heterozygous mutation facilitates tumor development and homozygous mutation is embryonically lethal in a mouse model where p53 is targeted deleted in the mammary gland and BRCA1 deletion is varied according to the required zygosity <ref name='p22172724'/>. High impact in yeast two-hybrid assay <ref name='p16403807'/></ref>.


==Impacted biological activities==
==Impacted biological activities==