6hth: Difference between revisions

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'''Unreleased structure'''


The entry 6hth is ON HOLD  until Paper Publication
==Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 5==
 
<StructureSection load='6hth' size='340' side='right' caption='[[6hth]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
Authors: Shaik, T.B., Marek, M., Romier, C.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6hth]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HTH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HTH FirstGlance]. <br>
Description: Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 5
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GQN:4-methoxy-~{N}-oxidanyl-3-[(4-phenylphenyl)carbonylamino]benzamide'>GQN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hth OCA], [http://pdbe.org/6hth PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hth RCSB], [http://www.ebi.ac.uk/pdbsum/6hth PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hth ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Histone deacetylase]]
[[Category: Marek, M]]
[[Category: Romier, C]]
[[Category: Romier, C]]
[[Category: Marek, M]]
[[Category: Shaik, T B]]
[[Category: Shaik, T.B]]
[[Category: Epigenetic]]
[[Category: Hdac8]]
[[Category: Hydrolase]]
[[Category: Pathogen]]
[[Category: Selective inhibitor]]

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