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==Crystal structure of Schistosoma mansoni HDAC8 complexed with Quisinostat== | |||
<StructureSection load='6hsh' size='340' side='right' caption='[[6hsh]], [[Resolution|resolution]] 1.54Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6hsh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HSH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HSH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOK:2-[4-[[(1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-~{N}-oxidanyl-pyrimidine-5-carboxamide'>GOK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hsh OCA], [http://pdbe.org/6hsh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hsh RCSB], [http://www.ebi.ac.uk/pdbsum/6hsh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hsh ProSAT]</span></td></tr> | |||
</table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Histone deacetylase]] | |||
[[Category: Marek, M]] | |||
[[Category: Romier, C]] | [[Category: Romier, C]] | ||
[[Category: | [[Category: Shaik, T B]] | ||
[[Category: | [[Category: Epigenetic]] | ||
[[Category: Hdac8]] | |||
[[Category: Hydrolase]] | |||
[[Category: Pathogen]] | |||
[[Category: Selective inhibitor]] | |||
Revision as of 09:58, 31 October 2018
Crystal structure of Schistosoma mansoni HDAC8 complexed with QuisinostatCrystal structure of Schistosoma mansoni HDAC8 complexed with Quisinostat
Structural highlights
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