2zav: Difference between revisions
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/za/2zav_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/za/2zav_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Christianson, D W]] | [[Category: Christianson, D W]] | ||
[[Category: Costanzo, L Di]] | [[Category: Costanzo, L Di]] | ||
[[Category: Alternative splicing]] | |||
[[Category: Apical water]] | [[Category: Apical water]] | ||
[[Category: Arginine metabolism]] | [[Category: Arginine metabolism]] | ||
[[Category: Cytoplasm]] | |||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Polymorphism]] | |||
[[Category: Proton wire]] | [[Category: Proton wire]] | ||
[[Category: Urea cycle]] | [[Category: Urea cycle]] | ||
Revision as of 12:23, 17 October 2018
Arginase I (homo sapiens): native and unliganded structure at 1.70 A resolutionArginase I (homo sapiens): native and unliganded structure at 1.70 A resolution
Structural highlights
Disease[ARGI1_HUMAN] Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.[1] [2] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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