6h7n: Difference between revisions

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'''Unreleased structure'''


The entry 6h7n is ON HOLD
==ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9==
 
<StructureSection load='6h7n' size='340' side='right' caption='[[6h7n]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Warne, T., Edwards, P.C., Dore, A.S., Leslie, A.G.W., Tate, C.G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6h7n]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H7N FirstGlance]. <br>
Description: ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=FVK:~{N}-[2-[[(2~{S})-2-oxidanyl-3-(4-oxidanylphenoxy)propyl]amino]ethyl]morpholine-4-carboxamide'>FVK</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h7n OCA], [http://pdbe.org/6h7n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h7n RCSB], [http://www.ebi.ac.uk/pdbsum/6h7n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h7n ProSAT]</span></td></tr>
[[Category: Leslie, A.G.W]]
</table>
[[Category: Edwards, P.C]]
== Function ==
[[Category: Tate, C.G]]
[[http://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. [[http://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA]] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
[[Category: Dore, A.S]]
__TOC__
</StructureSection>
[[Category: Dore, A S]]
[[Category: Edwards, P C]]
[[Category: Leslie, A G.W]]
[[Category: Tate, C G]]
[[Category: Warne, T]]
[[Category: Warne, T]]
[[Category: Activated]]
[[Category: Beta1 adrenoceptor]]
[[Category: Immune system]]
[[Category: Nanobody]]
[[Category: Partial agonist]]

Revision as of 11:11, 17 October 2018

ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9

Structural highlights

6h7n is a 6 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. [ADRB1_MELGA] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.

6h7n, resolution 2.50Å

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OCA