2y6c: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 1: Line 1:


==THE DISCOVERY OF MMP7 INHIBITORS EXPLOITING A NOVEL SELECTIVITY TRIGGER==
==The Discovery of MMP7 inhibitors Exploiting a Novel Selectivity Trigger==
<StructureSection load='2y6c' size='340' side='right' caption='[[2y6c]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2y6c' size='340' side='right' caption='[[2y6c]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==

Revision as of 12:21, 10 October 2018

The Discovery of MMP7 inhibitors Exploiting a Novel Selectivity TriggerThe Discovery of MMP7 inhibitors Exploiting a Novel Selectivity Trigger

Structural highlights

2y6c is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Activity:Matrilysin, with EC number 3.4.24.23
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[MMP7_HUMAN] Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.[1]

See Also

References

  1. ↑ Quantin B, Murphy G, Breathnach R. Pump-1 cDNA codes for a protein with characteristics similar to those of classical collagenase family members. Biochemistry. 1989 Jun 27;28(13):5327-34. PMID:2550050

2y6c, resolution 1.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2y6c&oldid=2957350"