2wrt: Difference between revisions
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== | ==The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26== | ||
<StructureSection load='2wrt' size='340' side='right' caption='[[2wrt]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2wrt' size='340' side='right' caption='[[2wrt]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/2wrt_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/2wrt_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Brophy, P M]] | [[Category: Brophy, P M]] | ||
[[Category: Isupov, M N]] | [[Category: Isupov, M N]] | ||
[[Category: | [[Category: LaCourse, E J]] | ||
[[Category: Line, K]] | [[Category: Line, K]] | ||
[[Category: Littlechild, J A]] | [[Category: Littlechild, J A]] | ||
Revision as of 12:48, 26 September 2018
The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26
Structural highlights
Function[GST26_FASHE] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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