6a9y: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
The | ==The crystal structure of Mu homology domain of SGIP1== | ||
<StructureSection load='6a9y' size='340' side='right' caption='[[6a9y]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6a9y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A9Y FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a9y OCA], [http://pdbe.org/6a9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a9y RCSB], [http://www.ebi.ac.uk/pdbsum/6a9y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a9y ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/SGIP1_HUMAN SGIP1_HUMAN]] May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Feng, Y]] | |||
[[Category: Liu, X]] | |||
[[Category: Dimer]] | |||
[[Category: Disulfide bond]] | |||
[[Category: Endocytosis]] | |||
[[Category: Sgip1]] | |||
Revision as of 10:59, 26 September 2018
The crystal structure of Mu homology domain of SGIP1The crystal structure of Mu homology domain of SGIP1
Structural highlights
Function[SGIP1_HUMAN] May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis (By similarity). |
| ||||||||||||||