Signal recognition particle receptor: Difference between revisions

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<StructureSection load='' size='450' side='right' scene='48/485587/Cv/1' caption='Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion [[2fh5]]'>
<StructureSection load='' size='350' side='right' scene='48/485587/Cv/1' caption='Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion [[2fh5]]'>


'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum.  SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]].  SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain.  SRPR α subunit binds to SRP54 subunit of SRP complex.  SRPR β subunit is a transmembrane GTPase.  The bacterial SRPR is called '''FtsY'''.
'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum.  SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]].  SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain.  SRPR α subunit binds to SRP54 subunit of SRP complex.  SRPR β subunit is a transmembrane GTPase.  The bacterial SRPR is called '''FtsY'''.
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**[[1zu5]], [[1zu4]] – SRPR FtsY NG domain – ''Mycoplasma mycoides''<br />
**[[1zu5]], [[1zu4]] – SRPR FtsY NG domain – ''Mycoplasma mycoides''<br />
**[[1vma]] – SRPR FtsY – ''Thermotoga maritima''<br />
**[[1vma]] – SRPR FtsY – ''Thermotoga maritima''<br />
**[[2yhs]], [[2qy9]], [[1fts]] – EcSRPR FtsY NG domain – ''Escherichia coli''<br />
**[[6cy]] – EaSRPR FtsY – ''Elizabethkingia anopheles''<br />
**[[2q9a]] – EcSRPR FtsY <br />
**[[6cy5]] – EaSRPR FtsY NG domain + GDP<br />
**[[2q9c]], [[2q9b]] – EcSRPR FtsY NG domain + GMPPNP<br />
**[[2q9a]] – TaSRPR FtsY – ''Thermus aquaticus''<br />
**[[2q9c]], [[2q9b]] – TaSRPR FtsY NG domain + GMPPNP<br />
**[[2yhs]], [[2qy9]], [[1fts]], [[6cqp]] – EcSRPR FtsY NG domain – ''Escherichia coli''<br />
**[[6fqd]] – EcSRPR FtsY NG domain + GDP<br />
**[[6c58]], [[6cvd]], [[6dlx]] – EcSRPR FtsY NG domain + antibiotic<br />
**[[2iyl]] – EcSRPR FtsY residues 20-303 + GDP<br />
**[[2iyl]] – EcSRPR FtsY residues 20-303 + GDP<br />
**[[2xxa]] - EcSRPR FtsY NG domain + signal recognition particle protein residues 1-433 (mutant) + 4.5SRNA<br />
**[[2xxa]] - EcSRPR FtsY NG domain + signal recognition particle protein residues 1-433 (mutant) + 4.5SRNA<br />

Revision as of 19:47, 20 September 2018


Signal recognition particle receptor (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the signal recognition particle (SRP). SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called FtsY.

  • . Water molecules shown as red spheres.
  • .

Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion 2fh5

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3D structures of signal recognition particle receptor3D structures of signal recognition particle receptor

Updated on 20-September-2018

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman