6b0d: Difference between revisions
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==An E. coli DPS protein from ferritin superfamily== | |||
<StructureSection load='6b0d' size='340' side='right' caption='[[6b0d]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6b0d]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B0D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B0D FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b0d OCA], [http://pdbe.org/6b0d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b0d RCSB], [http://www.ebi.ac.uk/pdbsum/6b0d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b0d ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DPS_ECO57 DPS_ECO57]] During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and copper toxicity, thermal stress and acid and base shocks. Also shows a weak catalase activity (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Adam, J S]] | |||
[[Category: Ronan, K]] | |||
[[Category: Rui, W]] | [[Category: Rui, W]] | ||
[[Category: Ruslan, S]] | [[Category: Ruslan, S]] | ||
[[Category: | [[Category: Dna binding protein]] | ||
[[Category: Dna-protecting protein]] | |||
[[Category: Oxidoreductase]] |