Sequestosome: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
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== Structural highlights == | == Structural highlights == | ||
SQS is a multi-domain protein. SQS domain structure includes: <br /> | SQS is a multi-domain protein. SQS domain structure includes: <br /> | ||
PB1 domain which contains Phox and Berm1<br /> | *PB1 domain which contains Phox and Berm1<br /> | ||
ZZ-type zinc finger <br /> | *ZZ-type zinc finger <br /> | ||
SMIR – SOD interaction domain<br /> | *SMIR – SOD interaction domain<br /> | ||
TB – TRAF6 binding motif<br /> | *TB – TRAF6 binding motif<br /> | ||
LC3 – microtubule-associated protein 1 light chain 3B<br /> | *LC3 – microtubule-associated protein 1 light chain 3B<br /> | ||
LIR – interaction region<br /> | *LIR – interaction region<br /> | ||
UBA – ubiquitin association domain. | *UBA – ubiquitin association domain. | ||
== Relevance == | == Relevance == | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[1q02]], [[2jy7]], [[2jy8]], [[2k0b]], [[2knv]] – | [[1q02]], [[2jy7]], [[2jy8]], [[2k0b]], [[2knv]] – hSQS UBA domain – human - NMR<br /> | ||
[[3b0f]] – mSQS UBA domain – mouse <br /> | [[3b0f]] – mSQS UBA domain – mouse <br /> | ||
[[2rru]] – mSQS UBA domain - NMR<br /> | [[2rru]] – mSQS UBA domain - NMR<br /> | ||
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[[3ade]] – mSQS + KEAP-1 – mouse<br /> | [[3ade]] – mSQS + KEAP-1 – mouse<br /> | ||
[[4mjs]] – hSQS-1 PB1 domain + protein kinase C zeta type<br /> | [[4mjs]] – hSQS-1 PB1 domain + protein kinase C zeta type<br /> | ||
[[4uf8]], [[4uf9]] – hSQS-1 PB1 | [[4uf8]], [[4uf9]] – hSQS-1 PB1 domain – Cryo EM<br /> | ||
[[5yp7]], [[5yp8]], [[5ypa]], [[5ypb]], [[5ypc]], [[5ype]], [[5ypg]], [[5yph]], [[5ypi]] – hSQS-1 residues 126-180<br /> | |||