2rs9: Difference between revisions

Revision as of 11:34, 12 September 2018

Solution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptideSolution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptide

Structural highlights

2rs9 is a 2 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Related:	2d9e
Gene:	BRPF1, BR140 (HUMAN)
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.^[1] ^[2]

References

↑ Doyon Y, Cayrou C, Ullah M, Landry AJ, Cote V, Selleck W, Lane WS, Tan S, Yang XJ, Cote J. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Mol Cell. 2006 Jan 6;21(1):51-64. PMID:16387653 doi:10.1016/j.molcel.2005.12.007
↑ Ullah M, Pelletier N, Xiao L, Zhao SP, Wang K, Degerny C, Tahmasebi S, Cayrou C, Doyon Y, Goh SL, Champagne N, Cote J, Yang XJ. Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. Mol Cell Biol. 2008 Nov;28(22):6828-43. doi: 10.1128/MCB.01297-08. Epub 2008 Sep , 15. PMID:18794358 doi:10.1128/MCB.01297-08

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OCA

[1] Doyon Y, Cayrou C, Ullah M, Landry AJ, Cote V, Selleck W, Lane WS, Tan S, Yang XJ, Cote J. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Mol Cell. 2006 Jan 6;21(1):51-64. PMID:16387653 doi:10.1016/j.molcel.2005.12.007

[2] Ullah M, Pelletier N, Xiao L, Zhao SP, Wang K, Degerny C, Tahmasebi S, Cayrou C, Doyon Y, Goh SL, Champagne N, Cote J, Yang XJ. Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. Mol Cell Biol. 2008 Nov;28(22):6828-43. doi: 10.1128/MCB.01297-08. Epub 2008 Sep , 15. PMID:18794358 doi:10.1128/MCB.01297-08

[1]

[2]

@@ Line 11: / Line 11: @@
 == Function ==
 [[http://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
+==See Also==
+*[[Peregrin|Peregrin]]
 == References ==
 <references/>
@@ Line 19: / Line 22: @@
 [[Category: Nagashima, T]]
 [[Category: Qin, X]]
+[[Category: Structural genomic]]
 [[Category: Umehara, T]]
 [[Category: Yokoyama, S]]
@@ Line 27: / Line 31: @@
 [[Category: National project on protein structural and functional analyse]]
 [[Category: Nppsfa]]
-[[Category: Structural genomic]]
 [[Category: Rsgi]]
 [[Category: Transcription]]
 [[Category: Transcription activator]]

2rs9: Difference between revisions

Revision as of 11:34, 12 September 2018

Solution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptideSolution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptide

Structural highlights

Function

See Also

References

Contents

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2rs9: Difference between revisions

Revision as of 11:34, 12 September 2018

Solution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptideSolution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptide

Structural highlights

Function

See Also

References

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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