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==Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN)== | |||
<StructureSection load='6aym' size='340' side='right' caption='[[6aym]], [[Resolution|resolution]] 1.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6aym]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AYM FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aym OCA], [http://pdbe.org/6aym PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aym RCSB], [http://www.ebi.ac.uk/pdbsum/6aym PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aym ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/A0A1E7P7U4_CAMJU A0A1E7P7U4_CAMJU]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[SAAS:SAAS00679308] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Adenosylhomocysteine nucleosidase]] | |||
[[Category: Almo, S C]] | |||
[[Category: Bonanno, J B]] | |||
[[Category: Ducati, R G]] | |||
[[Category: Harijan, R K]] | |||
[[Category: Schramm, V L]] | |||
[[Category: Foodborne disease]] | |||
[[Category: Hydrolase]] | |||
[[Category: Mtan enzyme]] | |||
[[Category: Transferase]] | |||