Selenocysteine: Difference between revisions
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==Translation from UGA Stop Codon== | ==Translation from UGA Stop Codon== | ||
During translation of mRNA, UGA is normally interpreted as a stop codon. However, when a special Sec-insertion sequence (SECIS), a stem-loop structure, is present downstream (in the untranslated region in mammals), UGA is translated as Sec<ref name='21st' /><ref name='Palioura' />. This involves the interaction of this stem-loop structure with specialized elongation factors called SelB in bacteria and EFSec in humans<ref name='Palioura' />. | During translation of mRNA, UGA is normally interpreted as a stop codon. However, when a special Sec-insertion sequence (SECIS), a stem-loop structure, is present downstream (in the untranslated region in mammals), UGA is translated as Sec<ref name='21st' /><ref name='Palioura' />. This involves the interaction of this stem-loop structure with specialized elongation factors called [[SelB]] in bacteria and EFSec in humans<ref name='Palioura' />. | ||
==Structure and Synthesis== | ==Structure and Synthesis== | ||