2it3: Difference between revisions

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==Structure of PH1069 protein from Pyrococcus horikoshii==
==Structure of PH1069 protein from Pyrococcus horikoshii==
<StructureSection load='2it3' size='340' side='right' caption='[[2it3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2it3' size='340' side='right' caption='[[2it3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2it2|2it2]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2it2|2it2]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2it3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2it3 OCA], [http://pdbe.org/2it3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2it3 RCSB], [http://www.ebi.ac.uk/pdbsum/2it3 PDBsum], [http://www.topsan.org/Proteins/RSGI/2it3 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2it3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2it3 OCA], [http://pdbe.org/2it3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2it3 RCSB], [http://www.ebi.ac.uk/pdbsum/2it3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2it3 ProSAT], [http://www.topsan.org/Proteins/RSGI/2it3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/2it3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/2it3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>

Revision as of 11:33, 4 July 2018

Structure of PH1069 protein from Pyrococcus horikoshiiStructure of PH1069 protein from Pyrococcus horikoshii

Structural highlights

2it3 is a 2 chain structure with sequence from 'pyrococcus shinkaii'. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[TYW31_PYRHO] S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.[HAMAP-Rule:MF_00266]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2it3, resolution 2.10Å

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OCA