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==Cryo-EM structure of GMPCPP-microtubule co-polymerised with doublecortin== | |||
<StructureSection load='6evw' size='340' side='right' caption='[[6evw]], [[Resolution|resolution]] 4.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6evw]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EVW FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6evw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evw OCA], [http://pdbe.org/6evw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6evw RCSB], [http://www.ebi.ac.uk/pdbsum/6evw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6evw ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_PIG TBB_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Sus scrofa]] | |||
[[Category: Manka, S W]] | |||
[[Category: Gtpase]] | |||
[[Category: Microtubule]] | |||
[[Category: Structural protein]] | |||
[[Category: Tubulin]] | |||
Revision as of 10:18, 4 July 2018
Cryo-EM structure of GMPCPP-microtubule co-polymerised with doublecortinCryo-EM structure of GMPCPP-microtubule co-polymerised with doublecortin
Structural highlights
Function[TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [TBB_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
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