2opw: Difference between revisions

Revision as of 08:44, 27 June 2018

Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)

Structural highlights

2opw is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:	PHYHD1 (HUMAN)
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PHYD1_HUMAN] Isoform 1 has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA. Isoform 2 and isoform 3 probably lack enzyme activity.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Zhang Z, Kochan GT, Ng SS, Kavanagh KL, Oppermann U, Schofield CJ, McDonough MA. Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase. Biochem Biophys Res Commun. 2011 May 20;408(4):553-8. doi:, 10.1016/j.bbrc.2011.04.059. Epub 2011 Apr 21. PMID:21530488 doi:10.1016/j.bbrc.2011.04.059

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OCA

[1] Zhang Z, Kochan GT, Ng SS, Kavanagh KL, Oppermann U, Schofield CJ, McDonough MA. Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase. Biochem Biophys Res Commun. 2011 May 20;408(4):553-8. doi:, 10.1016/j.bbrc.2011.04.059. Epub 2011 Apr 21. PMID:21530488 doi:10.1016/j.bbrc.2011.04.059

[1]

@@ Line 13: / Line 13: @@
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/2opw_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/2opw_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>

2opw: Difference between revisions

Revision as of 08:44, 27 June 2018

Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)

Structural highlights

Function

Evolutionary Conservation

References

Contents

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2opw: Difference between revisions

Revision as of 08:44, 27 June 2018

Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)

Structural highlights

Function

Evolutionary Conservation

References

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

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