Kisker lab: 5B5Q: Difference between revisions
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<scene name='78/781027/Panela/3'>Panel A:</scene> The overall structure, shown as cartoon, has a fold common to other deubiquitinases (green) with a helix inserted between strand 1 and 2 (yellow). The protein belongs to the family of cysteine proteases, in which an active-site cysteine initiates hydrolysis by acting as a nucleophile. Just like serine proteases, cystein proteases have a catalytic triad (i.e. three highly conserved residues in the active site). The catalytic triad is shown in all-bonds representation. | <scene name='78/781027/Panela/3'>Panel A:</scene> The overall structure, shown as cartoon, has a fold common to other deubiquitinases (green) with a helix inserted between strand 1 and 2 (yellow). The protein belongs to the family of cysteine proteases, in which an active-site cysteine initiates hydrolysis by acting as a nucleophile. Just like serine proteases, cystein proteases have a catalytic triad (i.e. three highly conserved residues in the active site). The catalytic triad is shown in all-bonds representation. | ||
(If you are new to proteopedia: Click on the green links in the text to see the scene in the 3D browser on the right. Use the mouse to change the view of the scene. Click on the controls on the bottom of the 3D browser to automatically spin the molecule, to resize the 3D browser window | (If you are new to proteopedia: Click on the green links in the text to see the scene in the 3D browser on the right. Use the mouse to change the view of the scene. Click on the controls on the bottom of the 3D browser to automatically spin the molecule, to make the rendering fancier (and perhaps slower), to resize the 3D browser window or to open a pop-up window with the same content. More controls become visible when you right-click inside the 3D browser area, and you can even remove parts of the scene or add to it using these controls.) | ||
===Related proteins=== | ===Related proteins=== | ||