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==The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state== | ==The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state== | ||
<StructureSection load='2gf0' size='340' side='right' caption='[[2gf0]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2gf0' size='340' side='right' caption='[[2gf0]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIRAS1, GBTS1, RIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIRAS1, GBTS1, RIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [http://pdbe.org/2gf0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf0 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [http://pdbe.org/2gf0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf0_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf0_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
Revision as of 09:40, 20 June 2018
The crystal structure of the human DiRas1 GTPase in the inactive GDP bound stateThe crystal structure of the human DiRas1 GTPase in the inactive GDP bound state
Structural highlights
Function[DIRA1_HUMAN] Displays low GTPase activity and exist predominantly in the GTP-bound form. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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