5whf: Difference between revisions

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'''Unreleased structure'''


The entry 5whf is ON HOLD until Paper Publication
==Crystal structure of vimentin coil 1B packed in a high-order filamentous form==
 
<StructureSection load='5whf' size='340' side='right' caption='[[5whf]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5whf]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WHF FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5whf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5whf OCA], [http://pdbe.org/5whf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5whf RCSB], [http://www.ebi.ac.uk/pdbsum/5whf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5whf ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/VIME_HUMAN VIME_HUMAN]] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.<ref>PMID:21746880</ref>  Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.<ref>PMID:21746880</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Obiero, J M]]
[[Category: Pang, A H]]
[[Category: Tsodikov, O V]]
[[Category: Coiled coil]]
[[Category: Helical domain]]
[[Category: Intermediate filament]]
[[Category: Oligomerization]]
[[Category: Structural protein]]

Revision as of 08:41, 20 June 2018

Crystal structure of vimentin coil 1B packed in a high-order filamentous formCrystal structure of vimentin coil 1B packed in a high-order filamentous form

Structural highlights

5whf is a 8 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[VIME_HUMAN] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.[1] Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.[2]

References

  1. ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11
  2. ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11

5whf, resolution 2.25Å

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