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==Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis==
==Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis==
<StructureSection load='2ew2' size='340' side='right' caption='[[2ew2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2ew2' size='340' side='right' caption='[[2ew2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ew2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew2 OCA], [http://pdbe.org/2ew2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ew2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ew2 PDBsum], [http://www.topsan.org/Proteins/MCSG/2ew2 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ew2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew2 OCA], [http://pdbe.org/2ew2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ew2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ew2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ew2 ProSAT], [http://www.topsan.org/Proteins/MCSG/2ew2 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ew2_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ew2_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>

Revision as of 12:12, 14 June 2018

Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalisCrystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis

Structural highlights

2ew2 is a 2 chain structure with sequence from Entfa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Activity:2-dehydropantoate 2-reductase, with EC number 1.1.1.169
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[Q831Q5_ENTFA] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).[RuleBase:RU003776]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2ew2, resolution 2.00Å

Drag the structure with the mouse to rotate

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OCA