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==Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant== | ==Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant== | ||
<StructureSection load='2f26' size='340' side='right' caption='[[2f26]], [[Resolution|resolution]] 1.58Å' scene=''> | <StructureSection load='2f26' size='340' side='right' caption='[[2f26]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1snt|1snt]], [[1so7|1so7]], [[1vcu|1vcu]], [[2f0z|2f0z]], [[2f10|2f10]], [[2f11|2f11]], [[2f12|2f12]], [[2f13|2f13]], [[2f24|2f24]], [[2f25|2f25]], [[2f27|2f27]], [[2f28|2f28]], [[2f29|2f29]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1snt|1snt]], [[1so7|1so7]], [[1vcu|1vcu]], [[2f0z|2f0z]], [[2f10|2f10]], [[2f11|2f11]], [[2f12|2f12]], [[2f13|2f13]], [[2f24|2f24]], [[2f25|2f25]], [[2f27|2f27]], [[2f28|2f28]], [[2f29|2f29]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f26 OCA], [http://pdbe.org/2f26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f26 RCSB], [http://www.ebi.ac.uk/pdbsum/2f26 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f26 OCA], [http://pdbe.org/2f26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f26 RCSB], [http://www.ebi.ac.uk/pdbsum/2f26 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2f26 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f26_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f26_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
Revision as of 12:00, 14 June 2018
Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double MutantCrystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant
Structural highlights
Function[NEUR2_HUMAN] Hydrolyzes sialylated compounds. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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