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==Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase from Campylobacter jejuni== | |||
<StructureSection load='6de8' size='340' side='right' caption='[[6de8]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6de8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DE8 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6de8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6de8 OCA], [http://pdbe.org/6de8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6de8 RCSB], [http://www.ebi.ac.uk/pdbsum/6de8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6de8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FOLD_CAMJE FOLD_CAMJE]] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.[HAMAP-Rule:MF_01576] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Structural genomic]] | |||
[[Category: Joachimiak, A]] | |||
[[Category: Kim, Y]] | |||
[[Category: Makowska-Grzyska, M]] | [[Category: Makowska-Grzyska, M]] | ||
[[Category: | [[Category: Peterson, S N]] | ||
[[Category: Zhang, R]] | [[Category: Zhang, R]] | ||
[[Category: | [[Category: Alpha-beta-fold]] | ||
[[Category: | [[Category: Csgid]] | ||
[[Category: | [[Category: Mthfdc]] | ||
[[Category: Oxidoreductase]] | |||
Revision as of 08:36, 30 May 2018
Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase from Campylobacter jejuniCrystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase from Campylobacter jejuni
Structural highlights
Function[FOLD_CAMJE] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.[HAMAP-Rule:MF_01576] |
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