Fibroblast growth factor receptor: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
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*FGFR1 | *FGFR1 | ||
*''FGFR1 tyrosine kinase domain'' | *''FGFR1 tyrosine kinase domain residues 458-765'' | ||
**[[1fgk]], [[3kxx]], [[3ky2]], [[4rwi]], [[5flf]] – hFGFR1 TKD (mutant) - human <br /> | **[[1fgk]], [[3kxx]], [[3ky2]], [[4rwi]], [[5flf]] – hFGFR1 TKD (mutant) - human <br /> | ||
**[[4uwy]] – hFGFR1 TKD <br /> | **[[4uwy]] – hFGFR1 TKD <br /> | ||
**[[4wun]], [[5am6]], [[5ew8]] – hFGFR1 TKD + inhibitor <br /> | **[[4wun]], [[5am6]], [[5ew8]], [[5o49]], [[5ora]] – hFGFR1 TKD + inhibitor <br /> | ||
**[[1agw]], [[1fgi]], [[2fgi]], [[3c4f]], [[3js2]], [[3rhx]], [[4f63]], [[4f64]], [[4f65]], [[3tt0]], [[4nk9]], [[4nka]], [[4nks]], [[5b7v]], [[5am7]], [[4rwj]], [[4rwk]], [[4rwl]], [[4uwb]], [[4uwc]], [[4zsa]], [[5uq0]] – hFGFR1 TKD (mutant) + inhibitor <br /> | **[[1agw]], [[1fgi]], [[2fgi]], [[3c4f]], [[3js2]], [[3rhx]], [[4f63]], [[4f64]], [[4f65]], [[3tt0]], [[4nk9]], [[4nka]], [[4nks]], [[5b7v]], [[5am7]], [[4rwj]], [[4rwk]], [[4rwl]], [[4uwb]], [[4uwc]], [[4zsa]], [[5uq0]], [[5vnd]], [[5ur1]] – hFGFR1 TKD (mutant) + inhibitor <br /> | ||
**[[3krj]] – hFGFR1 TKD residues 538-678, 753-922 (mutant) + inhibitor <br /> | **[[3krj]] – hFGFR1 TKD residues 538-678, 753-922 (mutant) + inhibitor <br /> | ||
**[[1xr0]] – hFGFR1 residues 409-430 + FGFR signaling adaptor N terminal - NMR<br /> | **[[1xr0]] – hFGFR1 residues 409-430 + FGFR signaling adaptor N terminal - NMR<br /> | ||
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**[[3gql]] – hFGFR1 TKD (mutant) + substrate <br /> | **[[3gql]] – hFGFR1 TKD (mutant) + substrate <br /> | ||
*''FGFR1 ligand-binding domain'' | *''FGFR1 ligand-binding domain D1 residues 35-208'' | ||
**[[2cr3]] – hFGFR1 LBD D1 - NMR<br /> | **[[2cr3]] – hFGFR1 LBD D1 - NMR<br /> | ||
**[[2ckn]] – FGFR1 LBD D1 – mouse - NMR<br /> | **[[2ckn]] – FGFR1 LBD D1 – mouse - NMR<br /> | ||
*''FGFR1 complex with FGF'' | *''FGFR1 D1 complex with FGF'' | ||
**[[5w59]] – hFGFR1 LBD D1 + FGF9<br /> | |||
*''FGFR1 D2,D3 residues 142-365 complex with FGF'' | |||
**[[3ojv]] – hFGFR1 LBD D2,D3 (mutant) + hFGF1 - human <br /> | **[[3ojv]] – hFGFR1 LBD D2,D3 (mutant) + hFGF1 - human <br /> | ||
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**[[1evt]] – hFGFR1 LBD D2,D3 + hFGF1 <br /> | **[[1evt]] – hFGFR1 LBD D2,D3 + hFGF1 <br /> | ||
**[[1fq9]] – hFGFR1 (mutant) LBD D2,D3 + hFGF2 (mutant) + HS<br /> | **[[1fq9]] – hFGFR1 (mutant) LBD D2,D3 + hFGF2 (mutant) + HS<br /> | ||
**[[5w21]] – hFGFR1 LBD D2,D3 + hFGF23 + klotho <br /> | |||
*FGFR2 | *FGFR2 | ||
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**[[4tye]], [[4tyg]], [[4tyi]], [[4tyj]] – hFGFR4 TKD <br /> | **[[4tye]], [[4tyg]], [[4tyi]], [[4tyj]] – hFGFR4 TKD <br /> | ||
**[[4qqj]], [[4qqt]] – hFGFR4 TKD (mutant) <br /> | **[[4qqj]], [[4qqt]] – hFGFR4 TKD (mutant) <br /> | ||
**[[5jkg]] – hFGFR4 TKD + inhibitor<br /> | **[[5jkg]], [[5nwz]], [[5nud]] – hFGFR4 TKD + inhibitor<br /> | ||
**[[4qrc]], [[4r6v]], [[4qqc]], [[4qq5]], [[4uxq]], [[4xcu]] – hFGFR4 TKD (mutant) + irreversible inhibitor<br /> | **[[4qrc]], [[4r6v]], [[4qqc]], [[4qq5]], [[4uxq]], [[4xcu]] – hFGFR4 TKD (mutant) + irreversible inhibitor<br /> | ||