2cib: Difference between revisions
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==High throughput screening and x-ray crystallography assisted evaluation of small molecule scaffolds for CYP51 inhibitors== | |||
<StructureSection load='2cib' size='340' side='right' caption='[[2cib]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='2cib' size='340' side='right' caption='[[2cib]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e9x|1e9x]], [[1ea1|1ea1]], [[1h5z|1h5z]], [[1u13|1u13]], [[1x8v|1x8v]], [[2bz9|2bz9]], [[2ci0|2ci0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e9x|1e9x]], [[1ea1|1ea1]], [[1h5z|1h5z]], [[1u13|1u13]], [[1x8v|1x8v]], [[2bz9|2bz9]], [[2ci0|2ci0]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cib OCA], [http://pdbe.org/2cib PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cib RCSB], [http://www.ebi.ac.uk/pdbsum/2cib PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cib OCA], [http://pdbe.org/2cib PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cib RCSB], [http://www.ebi.ac.uk/pdbsum/2cib PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cib ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/2cib_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/2cib_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||