2cs5: Difference between revisions

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==Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4==
==Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4==
<StructureSection load='2cs5' size='340' side='right' caption='[[2cs5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2cs5' size='340' side='right' caption='[[2cs5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs5 OCA], [http://pdbe.org/2cs5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cs5 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs5 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cs5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs5 OCA], [http://pdbe.org/2cs5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cs5 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cs5 ProSAT], [http://www.topsan.org/Proteins/RSGI/2cs5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2cs5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2cs5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>

Revision as of 11:06, 23 May 2018

Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4

Structural highlights

2cs5 is a 1 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:PTPN4 (HUMAN)
Activity:Protein-tyrosine-phosphatase, with EC number 3.1.3.48
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[PTN4_HUMAN] May act at junctions between the membrane and the cytoskeleton.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

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