DNA polymerase: Difference between revisions
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===Family X=== | ===Family X=== | ||
The thumb, palm, and fingers subdomains are a part of the of N-terminal, or 31-kDA polymerase fragment in the Family X Polymerases. The palm in this family contains three aspartic acid motifs. The fingers in this family have Helices M and N that contain amino acid residues. <ref>DOI:10.1016/j.bbapap.2009.07.008 </ref> | The thumb, palm, and fingers subdomains are a part of the of N-terminal, or 31-kDA polymerase fragment in the Family X Polymerases. The palm in this family contains three aspartic acid motifs. The fingers in this family have Helices M and N that contain amino acid residues. <ref>DOI:10.1016/j.bbapap.2009.07.008 </ref> The N-terminal is connected to an 8kDa amino terminal domain containing a 5' deoxyribose phosphate lyase that is required for base excision repair. Each member contains it's own structural differences that aid in it's functioning. <ref name="structure" /> | ||
===Family Y=== | ===Family Y=== | ||