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==Contracted Human Heavy-Chain Ferritin Crystal-Hydrogel Hybrid== | |||
<StructureSection load='6b8f' size='340' side='right' caption='[[6b8f]], [[Resolution|resolution]] 1.06Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6b8f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B8F FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> | ||
[[Category: Tezcan, F | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8f OCA], [http://pdbe.org/6b8f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b8f RCSB], [http://www.ebi.ac.uk/pdbsum/6b8f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8f ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ferroxidase]] | |||
[[Category: Bailey, J B]] | |||
[[Category: Subramanian, R]] | |||
[[Category: Tezcan, F A]] | |||
[[Category: Zhang, L]] | [[Category: Zhang, L]] | ||
[[Category: | [[Category: Hydrogel]] | ||
[[Category: | [[Category: Oxidoreductase]] | ||
[[Category: Polymer]] | |||
Revision as of 11:08, 2 May 2018
Contracted Human Heavy-Chain Ferritin Crystal-Hydrogel HybridContracted Human Heavy-Chain Ferritin Crystal-Hydrogel Hybrid
Structural highlights
Function[FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). |
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