1yz2: Difference between revisions

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==Solution structure of Am2766==
==Solution structure of Am2766==
<StructureSection load='1yz2' size='340' side='right' caption='[[1yz2]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
<StructureSection load='1yz2' size='340' side='right' caption='[[1yz2]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
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<table><tr><td colspan='2'>[[1yz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Conus_amadis Conus amadis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YZ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1yz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Conus_amadis Conus amadis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YZ2 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yz2 OCA], [http://pdbe.org/1yz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1yz2 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yz2 OCA], [http://pdbe.org/1yz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1yz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yz2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 09:31, 25 April 2018

Solution structure of Am2766Solution structure of Am2766

Structural highlights

1yz2 is a 1 chain structure with sequence from Conus amadis. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CO66_CONAA] Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.[1]

References

  1. ↑ Sudarslal S, Majumdar S, Ramasamy P, Dhawan R, Pal PP, Ramaswami M, Lala AK, Sikdar SK, Sarma SP, Krishnan KS, Balaram P. Sodium channel modulating activity in a delta-conotoxin from an Indian marine snail. FEBS Lett. 2003 Oct 9;553(1-2):209-12. PMID:14550575
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