5x8c: Difference between revisions
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<StructureSection load='5x8c' size='340' side='right' caption='[[5x8c]], [[Resolution|resolution]] 2.07Å' scene=''> | <StructureSection load='5x8c' size='340' side='right' caption='[[5x8c]], [[Resolution|resolution]] 2.07Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5x8c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X8C FirstGlance]. <br> | <table><tr><td colspan='2'>[[5x8c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X8C FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x86|5x86]], [[5x8a|5x8a]], [[5x8b|5x8b]], [[5x8d|5x8d]], [[5x8j|5x8j]], [[5x8k|5x8k]], [[5x8v|5x8v]], [[5x98|5x98]], [[5x99|5x99]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x86|5x86]], [[5x8a|5x8a]], [[5x8b|5x8b]], [[5x8d|5x8d]], [[5x8j|5x8j]], [[5x8k|5x8k]], [[5x8v|5x8v]], [[5x98|5x98]], [[5x99|5x99]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tmk, TTHA1607 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8c OCA], [http://pdbe.org/5x8c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x8c RCSB], [http://www.ebi.ac.uk/pdbsum/5x8c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8c ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8c OCA], [http://pdbe.org/5x8c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x8c RCSB], [http://www.ebi.ac.uk/pdbsum/5x8c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8c ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Thet8]] | |||
[[Category: DTMP kinase]] | [[Category: DTMP kinase]] | ||
[[Category: Chaudhary, S K]] | [[Category: Chaudhary, S K]] | ||
Revision as of 09:40, 18 April 2018
AMPPCP and TMP bound crystal structure of thymidylate kinase from thermus thermophilus HB8AMPPCP and TMP bound crystal structure of thymidylate kinase from thermus thermophilus HB8
Structural highlights
Function[KTHY_THET8] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. |
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