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==Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8== | ==Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8== | ||
<StructureSection load='1wkj' size='340' side='right' caption='[[1wkj]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1wkj' size='340' side='right' caption='[[1wkj]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkj OCA], [http://pdbe.org/1wkj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wkj RCSB], [http://www.ebi.ac.uk/pdbsum/1wkj PDBsum], [http://www.topsan.org/Proteins/RSGI/1wkj TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkj OCA], [http://pdbe.org/1wkj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wkj RCSB], [http://www.ebi.ac.uk/pdbsum/1wkj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkj ProSAT], [http://www.topsan.org/Proteins/RSGI/1wkj TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkj_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkj_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
Revision as of 19:41, 11 April 2018
Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8
Structural highlights
Function[NDK_THET8] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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