2gq7: Difference between revisions

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|PDB= 2gq7 |SIZE=350|CAPTION= <scene name='initialview01'>2gq7</scene>, resolution 1.6&Aring;
|PDB= 2gq7 |SIZE=350|CAPTION= <scene name='initialview01'>2gq7</scene>, resolution 1.6&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|LIGAND= <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=[[2g32|2g32]], [[2gpm|2gpm]], [[2gp4|2gp4]], [[2gq5|2gq5]], [[2gq6|2gq6]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gq7 OCA], [http://www.ebi.ac.uk/pdbsum/2gq7 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gq7 RCSB]</span>
}}
}}


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[[Category: Rypniewski, W.]]
[[Category: Rypniewski, W.]]
[[Category: Vallazza, M.]]
[[Category: Vallazza, M.]]
[[Category: CA]]
[[Category: GOL]]
[[Category: double helix]]
[[Category: double helix]]
[[Category: racemate]]
[[Category: racemate]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:07:42 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:20:01 2008''

Revision as of 03:20, 31 March 2008

File:2gq7.gif


PDB ID 2gq7

Drag the structure with the mouse to rotate
, resolution 1.6Å
Ligands: , , , ,
Related: 2g32, 2gpm, 2gp4, 2gq5, 2gq6


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of an RNA racemate


OverviewOverview

The racemate of the RNA duplex r(CUGGGCGG).r(CCGCCUGG) from Thermus flavus 5S rRNA has been crystallized and examined by X-ray crystallography. The space group is P1(_) with approximate unit-cell parameters a = 26.5, b = 38.0, c = 45.4 Angstrom, alpha = 113.1, beta = 100.5, gamma = 93.3 degrees. The structure was solved by molecular replacement. There are four RNA duplexes in the unit cell. The crystal lattice consists of columns of RNA duplexes. The duplexes are stacked end-to-end and are stabilized by intermolecular base-stacking interactions. Within each column the L-duplexes and D-duplexes are stacked alternately. Every other duplex in each stack has two alternative conformations, approximately equally occupied, corresponding to molecules oriented in opposite directions. Neighbouring columns are related by the crystallographic centre of symmetry. The unit cell also contains approximately 250 ordered water molecules and six ordered calcium ions. A glycerol molecule is visible in the minor groove interacting with a guanosine residue.

About this StructureAbout this Structure

2GQ7 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

ReferenceReference

The first crystal structure of an RNA racemate., Rypniewski W, Vallazza M, Perbandt M, Klussmann S, Delucas LJ, Betzel C, Erdmann VA, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):659-64. Epub 2006, May 12. PMID:16699193

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