Proteopedia

Bromodomain-containing protein: Difference between revisions

← Older editNewer edit →
Joel L. Sussman (talk | contribs)
ConfirmAccount, Editor, Journal, Mutation, Print3D, Tester, Bureaucrats, Administrators
7,980 edits
No edit summary
Michal Harel (talk | contribs)
31,761 edits
No edit summary
Line 22: Line 22:
*Bromodomain-containing protein 1
*Bromodomain-containing protein 1


**[[3lyi]] – hBRD1 PWWP domain - human<br />
**[[3lyi]] – hBRD1 PWWP domain residues 925-1049 - human<br />
**[[2ku3]] – hBRD1 PHD1 zinc finger domain - NMR<br />
**[[2ku3]] – hBRD1 PHD1 zinc finger domain residues 208-269 - NMR<br />
**[[2lq6]] – hBRD1 PHD2 zinc finger domain (mutant) - NMR<br />
**[[2lq6]] – hBRD1 PHD2 zinc finger domain residues 317-394 (mutant) - NMR<br />
**[[3l43]] – histone H3.3 N-terminal/hBRD1 PHD1 zinc finger domain - NMR<br />
**[[3l43]] – histone H3.3 N-terminal/hBRD1 PHD1 zinc finger domain - NMR<br />
**[[3rcw]] – hBRD1 bromodomain <br />
**[[3rcw]], [[4z02]] – hBRD1 bromodomain residues 555-688<br />
**[[5pwb]], [[5pwa]], [[5pw9]], [[5pw8]], [[5pw7]], [[5pw6]], [[5pw5]], [[5pw4]], [[5pw3]], [[5pw2]], [[5pw1]], [[5pw0]], [[5pvz]], [[5pvy]], [[5pvx]], [[5pvw]], [[5pvv]], [[5pvu]], [[5pvt]], [[5pvs]], [[5pvr]], [[5pvq]], [[5pvp]], [[5pvo]], [[5pvn]], [[5pvm]], [[5pvl]], [[5pvk]], [[5pvj]], [[5pvi]], [[5pvh]], [[5pvg]], [[5pvf]], [[5pve]], [[5pvd]], [[5pvc]], [[5pvb]], [[5pva]], [[5pv9]], [[5pv8]], [[5pv7]], [[5pv6]], [[5pv5]], [[5pv4]], [[5pv3]], [[5pv2]], [[5pv1]], [[5pv0]], [[5puz]], [[5puy]], [[5pux]], [[5puw]], [[5puv]], [[5puu]], [[5put]], [[5pus]], [[5pur]], [[5puq]], [[5pup]], [[5pun]], [[5pum]], [[5puo]], [[5pul]], [[5puk]], [[5puj]], [[5pui]], [[5puh]], [[5pug]], [[5puf]], [[5pue]], [[5pud]], [[5puc]], [[5pub]], [[5pua]], [[5pu9]], [[5pu8]], [[5pu7]], [[5pu6]], [[5pu5]], [[5pu4]], [[5pu3]], [[5pu2]], [[5pu1]], [[5pu0]], [[5ptz]], [[5pty]], [[5ptx]], [[5ptw]], [[5ptv]], [[5ptu]], [[5pts]], [[5ptt]], [[5ptr]], [[5ptq]], [[5ptp]], [[5pto]], [[5ptn]], [[5ptm]], [[5ptl]], [[5ptk]], [[5ptj]], [[5pth]], [[5ptg]], [[5ptf]], [[5pte]], [[5ptd]], [[5ptc]], [[5ptb]], [[5pta]], [[5pt9]], [[5pt8]], [[5pt7]] – [[5pnx]] – hBRD1 bromodomain (mutant)<br />
**[[5n49]] – hBRD1 bromodomain + inhibitor<br />
**[[5ame]] – hBRD1 bromodomain+PHD (mutant) + piperazine derivative<br />
**[[5ame]] – hBRD1 bromodomain+PHD (mutant) + piperazine derivative<br />
**[[5amf]] – hBRD1 bromodomain+PHD (mutant) + indazole derivative<br />
**[[5amf]] – hBRD1 bromodomain+PHD (mutant) + indazole derivative<br />
**[[5fg6]] – hBRD1 bromodomain+PHD + probe<br />
**[[5fg6]] – hBRD1 bromodomain+PHD + probe<br />
**[[4z02]] – hBRD1 residues 925-1049 + quinoline derivative<br />
**[[4z02]] – hBRD1 PWWP domain + quinoline derivative<br />


*Bromodomain-containing protein 2
*Bromodomain-containing protein 2


**[[1x0j]], [[2dvv]] – hBRD2 N-terminal bromodomain <br />
**[[1x0j]], [[2dvv]] – hBRD2 bromodomain 1<br />
**[[5hel]], [[5hem]], [[5hen]], [[5hfq]] – hBRD2 N-terminal bromodomain (mutant)<br />
**[[5hel]], [[5hem]], [[5hen]], [[5hfq]] – hBRD2 bromodomain 1 (mutant)<br />
**[[2g4a]] – hBRD2 residues 1-116 - NMR<br />
**[[2g4a]] – hBRD2 residues 1-116 - NMR<br />
**[[5ibn]] – hBRD2 bromodomain 2 <br />
**[[5ibn]] – hBRD2 bromodomain 2 <br />
Line 42: Line 44:
*Bromodomain-containing protein 2 complex
*Bromodomain-containing protein 2 complex


**[[2dvq]], [[2dvr]], [[2dvs]], [[2e3k]] – hBRD2 N-terminal bromodomain + histone H4 peptide<br />
**[[2dvq]], [[2dvr]], [[2dvs]], [[2e3k]] – hBRD2 bromodomain 1 + histone H4 peptide<br />
**[[3oni]] – hBRD2 residues 224-335 + inhibitor<br />
**[[3oni]] – hBRD2 residues 224-335 + inhibitor<br />
**[[3aqa]], [[2ydw]], [[2yek]], [[4a9e]], [[4a9f]], [[4a9h]], [[4a9i]], [[4a9j]], [[4a9m]], [[4a9n]], [[4a9o]], [[4alh]], [[4akn]], [[4alg]], [[4uyf]], [[4uyg]], [[4uyh]] – hBRD2 N-terminal bromodomain + inhibitor<br />
**[[3aqa]], [[2ydw]], [[2yek]], [[4a9e]], [[4a9f]], [[4a9h]], [[4a9i]], [[4a9j]], [[4a9m]], [[4a9n]], [[4a9o]], [[4alh]], [[4akn]], [[4alg]], [[4uyf]], [[4uyg]], [[4uyh]] – hBRD2 N-terminal bromodomain + inhibitor<br />
**[[4mr5]], [[4mr6]], [[4j1p]], [[5ig6]], [[5ek9]], [[5dw1]] – hBRD2 bromodomain 2 + inhibitor<br />
**[[4mr5]], [[4mr6]], [[4j1p]], [[5ig6]], [[5ek9]], [[5dw1]], [[5xhk]], [[5xhe]], [[5u6v]], [[5n2l]] – hBRD2 bromodomain 2 + inhibitor<br />
**[[5o3i]], [[5o3h]], [[5o3g]], [[5o3f]], [[5o3e]], [[5o3d]], [[5o3c]], [[5o3b]], [[5o3a]], [[5o39]], [[5o38]] – hBRD2 bromodomain 2 (mutant) + inhibitor<br />
**[[5u5s]] – hBRD2 bromodomain 2 + STAT3 peptide - NMR<br />
**[[5bt5]] – hBRD2 bromodomain 2 + probe<br />
**[[5bt5]] – hBRD2 bromodomain 2 + probe<br />
**[[4qev]], [[4qew]] – hBRD2 bromodomain 2 (mutant) + probe<br />
**[[4qev]], [[4qew]] – hBRD2 bromodomain 2 (mutant) + probe<br />
Line 61: Line 65:
**[[5hjc]] – hBRD3 bromodomain 2+ histone H3.1 peptide<br />
**[[5hjc]] – hBRD3 bromodomain 2+ histone H3.1 peptide<br />
**[[5a7c]] – hBRD3 bromodomain 2 + inhibitor<br />
**[[5a7c]] – hBRD3 bromodomain 2 + inhibitor<br />
**[[6bgh]] – hBRD3 ET domain + BRG1 peptide - NMR<br />
**[[6bgg]] – hBRD3 ET domain + CHD4 peptide - NMR<br />


*Bromodomain-containing protein 4
*Bromodomain-containing protein 4
Line 67: Line 73:
**[[2ouo]] – hBRD4 bromodomain 2<br />
**[[2ouo]] – hBRD4 bromodomain 2<br />
**[[2i8n]] – hBRD4 bromodomain 2 - NMR<br />
**[[2i8n]] – hBRD4 bromodomain 2 - NMR<br />
**[[6bnh]] – hBRD4 ET domain + JMJD6 peptide - NMR<br />
**[[3jvj]] – mBRD4 bromodomain 1<br />
**[[3jvj]] – mBRD4 bromodomain 1<br />
**[[2dww]], [[3jvl]], [[3jvm]] – mBRD4 bromodomain 2<br />
**[[2dww]], [[3jvl]], [[3jvm]] – mBRD4 bromodomain 2<br />
Line 77: Line 84:
**[[4kv1]] – hBRD4 bromodomain 1 + Rel peptide<br />
**[[4kv1]] – hBRD4 bromodomain 1 + Rel peptide<br />
**[[3mxf]] – mBRD4 bromodomain 1 + inhibitor<br />
**[[3mxf]] – mBRD4 bromodomain 1 + inhibitor<br />
**[[3p5o]], [[2yel]], [[3zyu]], [[3u5j]], [[3u5k]], [[3u5l]], [[4a9l]], [[4e96]], [[4f3i]], [[4hxk]], [[4hxl]], [[4hxm]], [[4hxn]], [[4hxo]], [[4hxp]], [[4hxr]], [[4hxs]], [[4lr6]], [[4lrg]], [[3svf]], [[3svg]], [[4gpj]], [[4hbv]], [[4hbw]], [[4hbx]], [[4hby]], [[4don]], [[4j0r]], [[4j0s]], [[4bw1]], [[4bw2]], [[4bw3]], [[4bw4]], [[4men]], [[4meo]], [[4mep]], [[4meq]], [[4bjx]], [[4c66]], [[4c67]], [[4ioo]], [[4ioq]], [[4ior]], [[4mr3]], [[4mr4]], [[4nqm]], [[4nr8]], [[4cfk]], [[4cfl]], [[4lyw]], [[4ogi]], [[4ogj]], [[4o70]], [[4o71]], [[4o72]], [[4o74]], [[4o75]], [[4o76]], [[4o77]], [[4o78]], [[4o7a]], [[4o7b]], [[4o7c]], [[4o7e]], [[4o7f]], [[4ps5]], [[4nuc]], [[4nue]], [[4nud]], [[4pce]], [[4pci]], [[4uyd]], [[4qzs]], [[4wiv]], [[4cl9]], [[4clb]], [[4xy9]], [[4xya]], [[4z1q]], [[4z1s]], [[4uix]], [[4uiy]], [[4uiz]], [[4qr3]], [[4qr4]], [[4qr5]], [[5bt4]], [[5a5s]], [[5a85]], [[5acy]], [[4x2i]], [[4zc9]], [[5fbx]], [[4yh3]], [[4yh4]], [[5coi]], [[5cp5]], [[5cpe]], [[5cqt]], [[5crm]], [[5crz]], [[5cs8]], [[5ctl]], [[5cy9]], [[5d0c]], [[5dx4]], [[4lzs]], [[5d24]], [[5d25]], [[5d26]], [[5d3h]], [[5d3j]], [[5d3l]], [[5d3n]], [[5d3p]], [[5d3r]], [[5d3s]], [[5d3t]], [[5egu]], [[5ei4]], [[5eis]], [[5hls]], [[5hm0]], [[5ku3]], [[5khm]], [[5i88]], [[5i80]], [[5f63]], [[5f62]], [[5f61]], [[5f60]], [[5e0r]], [[5dw2]], [[5dlz]], [[5dlx]], [[5cfw]], [[5ad3]], [[5ad2]], [[4zw1]], [[5u2f]], [[5u2e]], [[5u28]], [[5luu]], [[5lj2]], [[5lj1]] – hBRD4 bromodomain 1 + inhibitor<br />
**[[3p5o]], [[2yel]], [[3zyu]], [[3u5j]], [[3u5k]], [[3u5l]], [[4a9l]], [[4e96]], [[4f3i]], [[4hxk]], [[4hxl]], [[4hxm]], [[4hxn]], [[4hxo]], [[4hxp]], [[4hxr]], [[4hxs]], [[4lr6]], [[4lrg]], [[3svf]], [[3svg]], [[4gpj]], [[4hbv]], [[4hbw]], [[4hbx]], [[4hby]], [[4don]], [[4j0r]], [[4j0s]], [[4bw1]], [[4bw2]], [[4bw3]], [[4bw4]], [[4men]], [[4meo]], [[4mep]], [[4meq]], [[4bjx]], [[4c66]], [[4c67]], [[4ioo]], [[4ioq]], [[4ior]], [[4mr3]], [[4mr4]], [[4nqm]], [[4nr8]], [[4cfk]], [[4cfl]], [[4lyw]], [[4ogi]], [[4ogj]], [[4o70]], [[4o71]], [[4o72]], [[4o74]], [[4o75]], [[4o76]], [[4o77]], [[4o78]], [[4o7a]], [[4o7b]], [[4o7c]], [[4o7e]], [[4o7f]], [[4ps5]], [[4nuc]], [[4nue]], [[4nud]], [[4pce]], [[4pci]], [[4uyd]], [[4qzs]], [[4wiv]], [[4cl9]], [[4clb]], [[4xy9]], [[4xya]], [[4z1q]], [[4z1s]], [[4uix]], [[4uiy]], [[4uiz]], [[4qr3]], [[4qr4]], [[4qr5]], [[5bt4]], [[5a5s]], [[5a85]], [[5acy]], [[4x2i]], [[4zc9]], [[5fbx]], [[4yh3]], [[4yh4]], [[5coi]], [[5cp5]], [[5cpe]], [[5cqt]], [[5crm]], [[5crz]], [[5cs8]], [[5ctl]], [[5cy9]], [[5d0c]], [[5dx4]], [[4lzs]], [[5d24]], [[5d25]], [[5d26]], [[5d3h]], [[5d3j]], [[5d3l]], [[5d3n]], [[5d3p]], [[5d3r]], [[5d3s]], [[5d3t]], [[5egu]], [[5ei4]], [[5eis]], [[5hls]], [[5hm0]], [[5ku3]], [[5khm]], [[5i88]], [[5i80]], [[5f63]], [[5f62]], [[5f61]], [[5f60]], [[5e0r]], [[5dw2]], [[5dlz]], [[5dlx]], [[5cfw]], [[5ad3]], [[5ad2]], [[4zw1]], [[5u2f]], [[5u2e]], [[5u28]], [[5luu]], [[5lj2]], [[5lj1]], [[5y1y]], [[5wuu]], [[5vom]], [[5v67]], [[5uvw]], [[5ula]], [[5ti7]], [[5n2m]], [[5mli], [[5mkz]]], [[5m3a]], [[5m39]], [[5lrq]], [[5kj0]], [[5kdh]], [[5h21]], [[5f5z] – hBRD4 bromodomain 1 + inhibitor<br />
**[[5z9c]] – hBRD4 bromodomain 1 + inhibitor - NMR<br />
**[[5ti6]], [[5ti5]], [[5ti4]], [[5ti3]], [[5ti2]] – hBRD4 bromodomain 1 (mutant) + inhibitor <br />
**[[4lys]], [[4lzr]] – hBRD4 bromodomain 1 + colchiceine<br />
**[[4lys]], [[4lzr]] – hBRD4 bromodomain 1 + colchiceine<br />
**[[4qb3]] – hBRD4 bromodomain 1 + olinone<br />
**[[4qb3]] – hBRD4 bromodomain 1 + olinone<br />
Line 86: Line 95:
*Bromodomain-containing protein 4 bromodomain 2 complex
*Bromodomain-containing protein 4 bromodomain 2 complex


**[[2yem]], [[4z93]], [[5u2c]], [[5jwm]] – hBRD4 bromodomain 2 + inhibitor<br />
**[[2yem]], [[4z93]], [[5u2c]], [[5jwm]], [[5uvz]], [[5uvy]], [[5uvx]], [[5uvv]], [[5uvu]], [[5uvt]], [[5uvs]], [[5uoo]], [[5uf0]], [[5uez]], [[5uey]], [[5uex]], [[5uew]], [[5uev]], [[5ueu]], [[5uet]], [[5ues]], [[5uer]], [[5ueq]], [[5uep]], [[5ueo]] – hBRD4 bromodomain 2 + inhibitor<br />
**[[2lsp]] – hBRD4 bromodomain 2 + Nf-Kb peptide<br />
**[[2lsp]] – hBRD4 bromodomain 2 + Nf-Kb peptide<br />
**[[4kv4]] – hBRD4 bromodomain 2 + Rel peptide<br />
**[[4kv4]] – hBRD4 bromodomain 2 + Rel peptide<br />
**[[2mjv]] – hBRD4 bromodomain 2 + Twist peptide<br />
**[[2mjv]] – hBRD4 bromodomain 2 + Twist peptide<br />
**[[5t35]] – hBRD4 bromodomain 2 + ELOB + ELOC + PVHL peptide<br />
*Bromodomain-containing protein 7
**[[5mq1]] – hBRD7 bromodomain + inhibitor<br />


*Bromodomain-containing protein 9
*Bromodomain-containing protein 9
Line 97: Line 111:
**[[5ign]] – hBRD9 bromodomain + L999 <br />
**[[5ign]] – hBRD9 bromodomain + L999 <br />
**[[5igm]] – hBRD9 bromodomain + bromosporine <br />
**[[5igm]] – hBRD9 bromodomain + bromosporine <br />
**[[4nqn]], [[4xy8]], [[4z6h]], [[4z6i]], [[5e9v]], [[5f2p]], [[5f25]], [[5f1l]], [[5f1h]], [[5eu1]] – hBRD9 bromodomain + inhibitor<br />
**[[4nqn]], [[4xy8]], [[4z6h]], [[4z6i]], [[5e9v]], [[5f2p]], [[5f25]], [[5f1l]], [[5f1h]], [[5eu1]], [[5mky]] – hBRD9 bromodomain + inhibitor<br />
**[[4yy4]] – hBRD9 bromodomain + DMSO<br />
**[[4yy4]] – hBRD9 bromodomain + DMSO<br />
**[[4yy6]], [[4yyd]], [[4yyg]], [[4yyh]], [[4yyj]], [[4yyk]], [[4yyi]] – hBRD9 bromodomain + histone H4 peptide<br />
**[[4yy6]], [[4yyd]], [[4yyg]], [[4yyh]], [[4yyj]], [[4yyk]], [[4yyi]] – hBRD9 bromodomain + histone H4 peptide<br />
**[[4uit]], [[4uiu]], [[4uiv]], [[4uiw]] – hBRD9 JUS-SPRY domain + inhibitor<br />
**[[4uit]], [[4uiu]], [[4uiv]], [[4uiw]] – hBRD9 JUS-SPRY domain + inhibitor<br />
**[[5i7y]], [[5i7x]], [[5i40]] – hBRD9 JUS-SPRY domain + inhibitor<br />
**[[5i7y]], [[5i7x]], [[5i40]] – hBRD9 JUS-SPRY domain + inhibitor<br />
**[[5twx]] – hBRD9 bromodomain residues 134-250 + heterobifunctional ligand<br />
}}
}}


Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman
Retrieved from "https://proteopedia.openfox.io/w/Bromodomain-containing_protein"