1ui9: Difference between revisions

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==Crystal analysis of chorismate mutase from thermus thermophilus==
==Crystal analysis of chorismate mutase from thermus thermophilus==
<StructureSection load='1ui9' size='340' side='right' caption='[[1ui9]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='1ui9' size='340' side='right' caption='[[1ui9]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ode|1ode]], [[1ufy|1ufy]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ode|1ode]], [[1ufy|1ufy]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ui9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ui9 OCA], [http://pdbe.org/1ui9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ui9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ui9 PDBsum], [http://www.topsan.org/Proteins/RSGI/1ui9 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ui9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ui9 OCA], [http://pdbe.org/1ui9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ui9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ui9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ui9 ProSAT], [http://www.topsan.org/Proteins/RSGI/1ui9 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ui/1ui9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ui/1ui9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>

Revision as of 10:57, 28 March 2018

Crystal analysis of chorismate mutase from thermus thermophilusCrystal analysis of chorismate mutase from thermus thermophilus

Structural highlights

1ui9 is a 1 chain structure with sequence from "flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971. The April 2010 RCSB PDB Molecule of the Month feature on Concanavalin A and Circular Permutation by David Goodsell is 10.2210/rcsb_pdb/mom_2010_4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Chorismate mutase, with EC number 5.4.99.5
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[AROH_THETH] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Helmstaedt K, Heinrich G, Merkl R, Braus GH. Chorismate mutase of Thermus thermophilus is a monofunctional AroH class enzyme inhibited by tyrosine. Arch Microbiol. 2004 Mar;181(3):195-203. Epub 2004 Jan 15. PMID:14727008 doi:http://dx.doi.org/10.1007/s00203-003-0639-z

1ui9, resolution 1.65Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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