6cnh: Difference between revisions

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-'''Unreleased structure'''
-The entry 6cnh is ON HOLD
+==Human PRPF4B in complex with Rebastinib==
+<StructureSection load='6cnh' size='340' side='right' caption='[[6cnh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors: Godoi, P.H.C., Santiago, A.S., Ramos, P.Z., Silva, P.N.B., Righetto, G.L., Guimaraes, C., Massirer, K.B., Arruda, P., Elkins, J.M., Edwards, A.M., Structural Genomics Consortium (SGC)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CNH FirstGlance]. <br>
-Description: Human PRPF4B in complex with Rebastinib
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-[[Category: Righetto, G.L]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cnh OCA], [http://pdbe.org/6cnh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cnh RCSB], [http://www.ebi.ac.uk/pdbsum/6cnh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cnh ProSAT]</span></td></tr>
-[[Category: Elkins, J.M]]
+</table>
-[[Category: Massirer, K.B]]
+== Function ==
-[[Category: Guimaraes, C]]
+[[http://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
-[[Category: Edwards, A.M]]
+__TOC__
-[[Category: Silva, P.N.B]]
+</StructureSection>
+[[Category: Non-specific serine/threonine protein kinase]]
 [[Category: Arruda, P]]
-[[Category: Structural Genomics Consortium (Sgc)]]
+[[Category: Counago, R M]]
-[[Category: Santiago, A.S]]
+[[Category: Edwards, A M]]
-[[Category: Ramos, P.Z]]
+[[Category: Elkins, J M]]
-[[Category: Godoi, P.H.C]]
+[[Category: Fala, A M]]
+[[Category: Gileadi, O]]
+[[Category: Godoi, P H.C]]
+[[Category: Guimaraes, C R.W]]
+[[Category: Massirer, K B]]
+[[Category: Ramos, P Z]]
+[[Category: Righetto, G L]]
+[[Category: Structural genomic]]
+[[Category: Salmazo, A P.T]]
+[[Category: Santiago, A S]]
+[[Category: Silva, P N.B]]
+[[Category: Dcc2036]]
+[[Category: Inhibitor]]
+[[Category: Kinase]]
+[[Category: Sgc]]
+[[Category: Transferase]]