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==Structural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilis==
==Structural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilis==
<StructureSection load='1s7h' size='340' side='right' caption='[[1s7h]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1s7h' size='340' side='right' caption='[[1s7h]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1s7h]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S7H FirstGlance]. <br>
<table><tr><td colspan='2'>[[1s7h]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S7H FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YKOF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YKOF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s7h OCA], [http://pdbe.org/1s7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s7h RCSB], [http://www.ebi.ac.uk/pdbsum/1s7h PDBsum], [http://www.topsan.org/Proteins/MCSG/1s7h TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s7h OCA], [http://pdbe.org/1s7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s7h RCSB], [http://www.ebi.ac.uk/pdbsum/1s7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1s7h ProSAT], [http://www.topsan.org/Proteins/MCSG/1s7h TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus globigii migula 1900]]
[[Category: Vibrio subtilis ehrenberg 1835]]
[[Category: Dementieva, I]]
[[Category: Dementieva, I]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak, A]]

Revision as of 09:45, 8 March 2018

Structural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilisStructural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilis

Structural highlights

1s7h is a 4 chain structure with sequence from "vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:YKOF ("Vibrio subtilis" Ehrenberg 1835)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[YKOF_BACSU] Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Binds thiamine via its HMP moiety.[1] [2]

References

  1. ↑ Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS. Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms. J Biol Chem. 2002 Dec 13;277(50):48949-59. Epub 2002 Oct 9. PMID:12376536 doi:http://dx.doi.org/10.1074/jbc.M208965200
  2. ↑ Schyns G, Potot S, Geng Y, Barbosa TM, Henriques A, Perkins JB. Isolation and characterization of new thiamine-deregulated mutants of Bacillus subtilis. J Bacteriol. 2005 Dec;187(23):8127-36. PMID:16291685 doi:http://dx.doi.org/187/23/8127

1s7h, resolution 2.20Å

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