2ffh: Difference between revisions

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|PDB= 2ffh |SIZE=350|CAPTION= <scene name='initialview01'>2ffh</scene>, resolution 3.2&Aring;
|PDB= 2ffh |SIZE=350|CAPTION= <scene name='initialview01'>2ffh</scene>, resolution 3.2&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene> and <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
|LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=[[1ffh|1FFH]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ffh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffh OCA], [http://www.ebi.ac.uk/pdbsum/2ffh PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ffh RCSB]</span>
}}
}}


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[[Category: Stroud, R M.]]
[[Category: Stroud, R M.]]
[[Category: Walter, P.]]
[[Category: Walter, P.]]
[[Category: CD]]
[[Category: SO4]]
[[Category: ffh]]
[[Category: ffh]]
[[Category: gtpase]]
[[Category: gtpase]]
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[[Category: srp54]]
[[Category: srp54]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:51:46 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:02:07 2008''

Revision as of 03:02, 31 March 2008

File:2ffh.gif


PDB ID 2ffh

Drag the structure with the mouse to rotate
, resolution 3.2Å
Ligands: ,
Related: 1FFH


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS


OverviewOverview

The crystal structure of the signal sequence binding subunit of the signal recognition particle (SRP) from Thermus aquaticus reveals a deep groove bounded by a flexible loop and lined with side chains of conserved hydrophobic residues. The groove defines a flexible, hydrophobic environment that is likely to contribute to the structural plasticity necessary for SRP to bind signal sequences of different lengths and amino acid sequence. The structure also reveals a helix-turn-helix motif containing an arginine-rich alpha helix that is required for binding to SRP RNA and is implicated in forming the core of an extended RNA binding surface.

About this StructureAbout this Structure

2FFH is a Single protein structure of sequence from Thermus aquaticus. Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of the signal sequence binding subunit of the signal recognition particle., Keenan RJ, Freymann DM, Walter P, Stroud RM, Cell. 1998 Jul 24;94(2):181-91. PMID:9695947

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