6fe4: Difference between revisions
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==Crystal structure of the complex between Shiga toxin Stx2 B subunit and neutralising Nb113== | |||
<StructureSection load='6fe4' size='340' side='right' caption='[[6fe4]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6fe4]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FE4 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fe4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fe4 OCA], [http://pdbe.org/6fe4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fe4 RCSB], [http://www.ebi.ac.uk/pdbsum/6fe4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fe4 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/STXB_BP933 STXB_BP933]] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bernedo, R]] | |||
[[Category: Muyldermans, S]] | [[Category: Muyldermans, S]] | ||
[[Category: Sterckx, Y | [[Category: Sterckx, Y G.J]] | ||
[[Category: | [[Category: Complex]] | ||
[[Category: Nanobody]] | |||
[[Category: Shiga]] | |||
[[Category: Toxin]] |