Adhesin: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 8: | Line 8: | ||
Bacterial pathogens use adhesins as a major factor in adhesion-based virulence. Adhesins serve as vaccine targets since they are essential to infection<ref>PMID:10341176</ref>. | Bacterial pathogens use adhesins as a major factor in adhesion-based virulence. Adhesins serve as vaccine targets since they are essential to infection<ref>PMID:10341176</ref>. | ||
== Structural highlights == | |||
*<scene name='70/705684/Cv/2'>Adhesin PsaA complex with galactose, acetate and tert-butyl formate</scene> (PDB ID [[4f8p]]).<ref>PMID:23277582</ref> | *<scene name='70/705684/Cv/2'>Adhesin PsaA complex with galactose, acetate and tert-butyl formate</scene> (PDB ID [[4f8p]]).<ref>PMID:23277582</ref> | ||
| Line 34: | Line 37: | ||
**[[3zk8]], [[3zk9]], [[3zka]] – SpPsaA (mutant)<br /> | **[[3zk8]], [[3zk9]], [[3zka]] – SpPsaA (mutant)<br /> | ||
**[[5cyl]] – PsaA subunit CUPB6 - ''Pseudomonas aeruginosa''<br /> | **[[5cyl]] – PsaA subunit CUPB6 - ''Pseudomonas aeruginosa''<br /> | ||
* Fimbrial adhesion complex | * Fimbrial adhesion complex | ||
| Line 52: | Line 48: | ||
**[[4f8o]] – YpPsaA + lactose + inhibitor <BR /> | **[[4f8o]] – YpPsaA + lactose + inhibitor <BR /> | ||
**[[4f8p]] – YpPsaA + galactose <BR /> | **[[4f8p]] – YpPsaA + galactose <BR /> | ||
*Epitheial adhesin | |||
**[[4d3w]], [[4asl]], [[4af9]] – CgAdh epithelial 1 A domain – ''Candida glabrata''<br /> | |||
**[[4afc]], [[4afb]], [[4afa]] – CgAdh epithelial 1 A domain (mutant)<br /> | |||
**[[4cp2]], [[4cp1]], [[4cp0]] – CgAdh epithelial 9 A domain <br /> | |||
**[[4coz]], [[4coy]], [[4cow]], [[4cov]], [[4cou]] – CgAdh epithelial 6 A domain <br /> | |||
*Collagen adhesin (CAdh) | *Collagen adhesin (CAdh) | ||