6aup: Difference between revisions

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-'''Unreleased structure'''
-The entry 6aup is ON HOLD  until Paper Publication
+==Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox==
+<StructureSection load='6aup' size='340' side='right' caption='[[6aup]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-Authors: Gewe, M.M., Rupert, P., Strong, R.K.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6aup]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AUP FirstGlance]. <br>
-Description: Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6au7|6au7]], [[6atl|6atl]], [[6atn|6atn]], [[6ats|6ats]], [[6atu|6atu]], [[6atw|6atw]], [[6aty|6aty]]</td></tr>
-[[Category: Strong, R.K]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aup OCA], [http://pdbe.org/6aup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aup RCSB], [http://www.ebi.ac.uk/pdbsum/6aup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aup ProSAT]</span></td></tr>
-[[Category: Gewe, M.M]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/KGX22_MESMA KGX22_MESMA]] Blocks human and/or rat Kv11.1/KCNH2/ERG1, Kv11.2/KCNH6/ERG2 and Kv11.3/KCNH7/ERG3 by binding to channel outer vestibule (S5P domain) with a 1:1 stoichiometry. Has also a minimal effect on rat ELK1/KCNH4 potassium channels.[UniProtKB:Q9BKB7]
+__TOC__
+</StructureSection>
+[[Category: Gewe, M M]]
 [[Category: Rupert, P]]
+[[Category: Strong, R K]]
+[[Category: Cystine knot]]
+[[Category: Knottin]]
+[[Category: Toxin]]